era7 bioinformatics R&D group

Using Uniprot Advanced search

This short post shows how to use Uniprot Advanced search to retrieve proteins of interest. In this Biostar question they want to retrieve human proteins with the domain “FYVE”

First click on Advanced search in Uniprot (www.uniprot.org) website

Then select Domain in the field box and type FYVE

Click then Add & Search and select now Organism in the Field box and type Homo sapiens.

Clicking again on Add & Search you get your set of proteins. And if you click on Download on the right you can download the data in several formats.

Similar searches (and more complex ones) can be done combining the logical operators and the available fields.